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While both Retatrutide and tirzepatide (known commercially as Zepbound) are Eli Lilly products targeting GLP-1 receptors, Retatrutide's additional action on GCG might promote greater appetite reduction and weight loss

55 Indeed, a more recent large meta-analysis confirmed that while GIPR variants may influence BMD, this does not necessarily translate to increased bone fracture risk

Then, one or two times per month for maintenance

When used together, these two peptides can enhance the bodys natural production of growth hormone, providing a synergistic effect that may lead to the stimulation of muscle growth and fat loss