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Finally, an important implication of the multidisciplinary model in the CMC is to enhance screening and treatment of obstructive sleep apnea (OSA), given its high prevalence among cardiometabolic patients (60%), the evidence of improved patient-centred outcomes and quality of life with OSA treatment in patients with CVD, and last but not least, OSA independent association with high levels of glucose and triglyceride levels in addition to markers of inflammation, arterial stiffness, and atherosclerosis (34, 35)
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In addition to activating GLP-1 receptors, tirzepatide also works at the glucose-dependent insulinotropic polypeptide (GIP) receptors to further improve blood sugar levels and reduce appetite Similarly, Retatrutide operates by targeting GLP-1 and GIP receptors
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Valuations for the two pharmaceutical companies (Novo Nordisk and Eli Lilly) at the core of this trend have rapidly increased as a result
