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While both vitamins are essential for overall health, they serve distinct roles in the body and complement semaglutide treatment differently

This is more modest than GLP-1 agonists but tends to be more sustainable with less muscle loss

Real-world data from clinics offering this combination protocol suggests enhanced fat loss compared to tirzepatide alone, but these observations come from uncontrolled clinical settings and cannot substitute for randomized controlled trials

Use within 120 days from when opened

Here is a breakdown: Most people are able to get enough vitamin B12 from their diets, Allen says, so widespread supplementation isn't necessary