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Also, given the observational nature of the study, we could expect the presence of indication bias, a type of confounding bias that occurs when a symptom or sign of disease is judged as an indication for a given therapy, and is therefore associated both with the use of a drug and with a higher probability of an outcome related to the disease for which the agent is indicated [37]

Thus, it was shown in studies performed in 1995 in cynomolgus monkeys and rats that valine-pyrrolidide reduces glucose excursion after an oral glucose load (26)

It does not cause masculinisation, weight gain, or hormonal disruption

However, there are some situations where these contractions may be a sign of a more serious underlying health condition or have the potential to cause harm: Chronic muscle spasms: If muscle spasms occur frequently and persist for an extended period, it may signify the presence of an underlying issue such as nerve damage or a neurological disorder