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van Dalen, van den Berg 2011)
3.1.2 Inflammasome and DAMPs inhibitors Since NLRP3 inflammasome activation and mtDNA-TLR9 are key drivers, pharmacological inhibition of these can be beneficial
The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation
g-i , Tumor metabolites from mice with orthotopically implanted HCC-1806 cells treated with bi-daily i.p
Headaches, hallucinations, hemiparesis, and seizures are some of the most prominent behavioral manifestations observed when CRS and ICANS occur secondary to brain-targeted CAR-T therapy (Shimabukuro-Vornhagen et al., 2018)
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