Nature Medicine, 2024 Jan5;30(1):168176
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In addition, increased HLA-II expression can lead to increased presentation of native cellular autoantigens or viral antigens, which can undergo posttranslational modifications, such as citrullination, and form neoantigens, through the endogenous antigen processing pathway, triggering the activation of autoreactive cells [171, 212,213,214,215]
Regina Castro of the Mayo Clinic wrote in an article for the institution's website that it is not yet certain why GLP-1 agonists help with weight loss, but they do curb hunger and can make a person eat less
The successful completion of Phase 1 trials provided the foundation for advancing Retatrutide through the clinical development process