DOI: 10.1007/s12325-025-03194-8 Hoog MM, Kan H, Deger KA, et al
Liver protein targets of hepatotoxic 4-bromophenol metabolites
Haplotypes of TCC, TTC, and TTT of rs1050450, rs3811699, and rs1800668 in GPX1 gene also had a significant link to KBD 68
Ageing is linked to changes in signalling throughout the NEI axis, such as decreased neuroimmune communication, endocrine imbalances that impair immune regulation, and impaired hypothalamicpituitaryadrenal (HPA) axis function
Additionally, GLP-1 suppresses glucagon secretion from pancreatic alpha cells, which decreases hepatic glucose production