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In the Nature study, researchers demonstrated that levodopa reversed the effects of inflammation on the brains functional connectivity in reward circuitry and anhedonia (inability to feel pleasure) in depressed individuals with higher C-reactive protein (CRP), a blood biomarker produced and released by the liver in response to inflammation
Iepsen EW, Have CT, Veedfald S, et al
Heliyon 8 (6), e09575
Key interconnections include: - Insulin resistance
Physicians should weigh the potential therapeutic benefits against the risk of adverse outcomes
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