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Many reproductive health providers recommend switching to a LARC when starting GLP-1 therapy if pregnancy prevention is critical

During the full time period (2018 2024), 70.9% of GLP-1 RA prescriptions had a dispense within 60 days of their prescription (e.g., were initiated within 60 days)

12 Nevertheless, curcumins effects on circulating GLP-1 have not yet been directly quantified in human trials, so its role as a GLP-1 targeted strategy remains speculative

The oral formulation almost certainly delivers less bioavailable peptide than equivalent injectable doses, but the delivered amount may still cross therapeutic thresholds for some individuals and conditions