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Most glutathione side effects are mild and gastrointestinal, but more serious reactions can occur in vulnerable populations
Recent expert consensus from 20232025 characterizes these medications as metabolic disease modifiers rather than simple glucose lowering agents
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In the U.S., for example, only 2% of the obese adult population were historically treated with anti-obesity drugs, due to a combination of lack of clarity about the role and value of pharmacotherapies (which were also less effective and sometimes with greater side effects than the recently launched treatments), limited insurance coverage and resulting out-of-pocket costs 12
Whether there is a point at which the muscle mass loss becomes detrimental remains unclear
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