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Extreme caloric restriction during the adaptation period compounds fatigue and can trigger muscle loss and metabolic slowdown
One of the vitamins to take while using tirzepatide is Vitamin B12, as it plays a key role in fat metabolism, aids in energy production and neurological function, and may improve weight loss
Tirzepatide 15 mg (Mounjaro/Zepbound) produced 22.5% mean weight loss at 72 weeks in SURMOUNT-1 (N=2,539) [14]
The three most recent Phase 3 readouts are: TRIUMPH-4 (December 2025) showing 28.7% weight reduction at 68 weeks in obesity with knee osteoarthritis, TRANSCEND-T2D-1 (March 2026) showing A1C reductions up to 2.0% and 16.8% weight loss at 40 weeks in type 2 diabetes, and TRIUMPH-1 (May 2026) showing up to 25.0% weight reduction at 80 weeks in the pivotal obesity trial
This is your chance to review your results, ask questions, and go over treatment options like Semaglutide and Tirzepatide, which can support your weight loss goals
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