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Gene therapy represents a promising avenue in oncology, using nucleic acids such as DNA, siRNA, mRNA, and shRNA to modulate gene expression in cancer cells [55]

Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency

Indicating a putative link between carnitine and serotonin, studies in mice have shown that carnitine supplementation increases serotonin concentration in the brain (32, 33)

Chemosensitivity tests have limitations due to their inability to mimic the exact conditions inside the body of an individual patient

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