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Mechanistically, T3 suppresses Cyp8b1 expression, resulting in increased the levels of Farnesoid X receptor (FXR)-antagonistic bile acids, thereby potentiating GLP-1 production and insulin secretion by repressing intestinal FXR signalling
Corsaro A, Paludi D, Villa V, D'Arrigo C, Chiovitti K, Thellung S, Russo C, Di Cola D, Ballerini P, Patrone E, Schettini G, Aceto A, Florio T.Chen, T., Xing, W., Xu, H., Zhang, D., Peng, Z., Ren, M.,
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The dynamic state of body constituents
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