Statistical analysis Using data generated from a pilot study and G*Power 3.1 software (Dsseldorf, Germany), it was determined that a sample size of 15 would provide 80% power to detect an increase in CNS GSH concentrations between pre- and post-administration values, with an accepted alpha value of 0.2
The fact that GLP-1R agonism can reduce Cyp2e1 levels independent of ethanol intake suggests that GLP-1R agonism may reduce ethanol metabolism and, therefore, result in higher serum ethanol levels
The region is becoming more accessible due to better medical infrastructure and the increasing adoption of GLP-1s in chronic disease programmes
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