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The most common symptoms of overt hyperthyroidism are 47: Weight loss despite a higher appetite Heart palpitations Nervousness Tremors Difficulty breathing Becoming easily fatigued Diarrhea Muscle weakness Heat intolerance Sweating more than usual Irregular menstrual cycles Factors that up the risk of overt hyperthyroidism commonly include: Too much dietary iodine 47 Iodine deficiency (which can lead to both hypo- and hyperthyroidism) 47 A family history of hyperthyroidism 47 Being female (its 10 times more likely to occur in women than men) 47 Metabolic syndrome and insulin resistance are associated with increased incidence of goiter and thyroid cancer 53 Treatment for Overt Hyperthyroidism Conventional treatment for overt hyperthyroidism includes taking radioactive iodine or antithyroid medication, or having part of the thyroid gland removed 47