In the Phase 2 obesity trial, which followed adults with obesity or overweight for 48 weeks, the average reductions in body weight were striking: To put that in perspective, at the 12 mg dose, more than eight in ten participants lost at least 15% of their starting body weight
Compare to injectable formats for protocol selection
Lipid panel if you have cardiovascular risk or high cholesterol
Looking forward, the GLP-1 drugs we study (semaglutide, tirzepatide, and emerging oral formulations like orforglipron) are likely only the beginning of a new wave of chronic therapies for conditions like obesity, heart failure, and even kidney disease
Another compounding trade group, the Alliance for Pharmacy Compounding, thanked the FDA for the grace period but insisted that the FDAs tirzepatide decision is not necessarily the end of the story. APC CEO Scott Brunner highlighted the ongoing litigation in a statement, writing that the agencys ruling was not a decision by a court. Its a unilateral action by the agency, so dont confuse the two, Brunner said, adding that he anticipated the court would also consider the perspective of compounders