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The GLP-1-producing preproglucagon (PPG) neurons located in the nucleus tractus solitarius (NTS) and the intermediate reticular nucleus of the medulla oblongata are the major source of endogenous GLP-1 in the central nervous system, which project widely throughout the central nervous system especially the autonomic control areas (Merchenthaler et al., 1999

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Many peptides can maintain activity for many years

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Gentiopicroside-induced gastric cancer necroptosis via the hif-1 signaling pathway: a study involving molecular docking and experimental validation