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Suppression of glucagon secretion Incretins also reduce glucagon release from alpha cells, decreasing hepatic glucose output
GLP-1
Isolated hepatocytes were plated on collagen-coated 6-well plates (4 10 4 cells per cm 2 ) in DMEM (Gibco #12800-017, containing 1 mM pyruvate, 25 mM glucose, and 4 mM glutamine) supplemented with 10 % (vol/vol) fetal bovine serum (FBS), 100 units/ml penicillin, 100 g/ml streptomycin, 1 M dexamethasone, 0.1 M insulin, and an additional 1 mM sodium pyruvate and incubated at 37 C in an atmosphere of 5 % CO 2
Further research is essential to elucidate the dynamic interplay between exercise, ferroptosis, and NAFLD, providing a solid theoretical basis and practical guidelines for exercise-based interventions targeting ferroptosis inhibition
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