FDA prescribing information for some GLP-1 receptor agonists (particularly those approved for weight management) includes recommendations to monitor heart rate at regular intervals and consider discontinuation for sustained increases in resting heart rate
According to study results, GLP-1RA use was associated with significantly higher rates of retained gastric content (OR = 5.56
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This symptom may be inconvenient or concerning, prompting patients to ask whether semaglutide is causing the problem, if its a sign that the medication is working, or whether it might be an indicator of an underlying issue
In July 2024, Roche, a Swiss-based pharmaceuticals company, acquired Carmot Therapeutics for US$ 2.7 billion (with up to US$ 400 million in additional milestone payments)