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42 Suppl 3, 2001, pp
Head to head comparison of GLP-1 analogs The clinical results achieved by short-, long, and prolonged-acting GLP-1 analogs have now been tested across different studies and in direct head to head comparison studies
In a randomized clinical trial, tesamorelin reduced visceral adipose tissue and liver fat in HIV-infected patients (Stanley et al., JAMA, 2014), and its Phase 3 program (Falutz et al.) established the visceral-fat effect that underpins its FDA approval
As a result, a meta-analysis of 13 RCTs revealed that GLP-1 RAs, including liraglutide, semaglutide, and dulaglutide, are associated with a 23% increased risk of rapid worsening of diabetic retinopathy in T2DM (OR, 1.23
Cell Metabolism, 34(9), 1234-1247.e9
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