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MZB have the potential to self-renew 18 and are activated more quickly than FoB 7,8 , properties consistent with a requirement for glycolytic reprogramming in activated B cells 101
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However, the low negative predictive values for the smartphone images reflect a missed NMSC in about 25% of lesions (42/170) which severely restricts its predictive value for any negative diagnosis of NMSC
This is especially important for those with genetic polymorphisms in glutathione genes
Medical supervision isnt a nice-to-have
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