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Data collected from a randomized, placebo-controlled, double-blind trial of liraglutide 3.0 mg, in which nausea was the most frequent adverse event, showed that greater weight loss was associated with transient nausea and vomiting in participants with obesity but without diabetes [50]
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Garzon R, Pichiorri F, Marcucci G, Kornblau S, Andreeff M , Croce C
The authors suggest that the GLP-1-estradiol compound allows targeted delivery of estradiol to the CNS
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