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Biomater Adv

Most Common Side Effects: Digestive Problems The most common side effects of semaglutide affect the digestive system

doi:10.1124/jpet.112.199497

Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist a medication that mimics the action of GLP-1, a naturally occurring hormone produced in the gut in response to eating

I would not recommend microdosing GLP-1s for individuals with significant amounts of weight to lose or known metabolic dysregulation. The bottom line is that there are still questions regarding the effectiveness and safety of microdosing GLP-1 medications, and this type of regimen is not for everyone