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Reviews focusing on semaglutide specifically [65] and broader examinations of GLP-1 RA mechanisms and clinical data have consistently concluded that these agents represent important therapeutic advances

Hemoglobin A1c levels typically rise within 3 months after discontinuation, and fasting and postprandial glucose levels increase as the medication's insulinotropic and glucagon-suppressing effects dissipate

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GLP-1 medications may be worth discussing with your provider if you have PMOS and one or more of these patterns: Insulin resistance, prediabetes, type 2 diabetes, or elevated fasting insulin

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