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Sleep architecture effect: Sermorelin = modest

The medication works by activating GLP-1 receptors in the hypothalamus and brainstem to reduce hunger signals, increase feelings of fullness, and slow gastric emptying, making it substantially more potent than nutritional supplements

The most common side effect is hypoglycemia: IGF-1 DES enhances glucose uptake into muscle cells and this can lead to a rapid drop in blood sugar levels, especially if youre already using insulin or training fasted

Inflammatory benefit requires consistent treatment adherence and realistic timelinesanti-inflammatory markers typically improve over 12-24 weeks, not immediately

Novo Nordisks Competitors The move also intensifies competition in the fast-growing GLP-1 market, where Novo Nordisk faces pressure from rival drugmaker Eli Lilly, which makes diabetes medication Mounjaro and weight-loss drug Zepbound