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Forschungsarbeiten zur oralen BPC-157-Gabe konzentrieren sich auf die gastroprotektive Wirkung bei direktem Schleimhautkontakt, die systemische Bioverfgbarkeit im Vergleich zur parenteralen Route und die Wirksamkeit bei Modellen entzndlicher Darmerkrankungen

GSH could detoxify heterogeneous substances under the catalysis of Glutathione S-transferases (GST), then secrete them via the multidrug resistance associated proteins (MRPs) efflux pump (Kuermanbayi et al., 2022)

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By selectively disrupting key antioxidant systemssuch as inhibiting glutathione synthesis with buthionine sulfoximine (BSO), blocking thioredoxin reductase with auranofin, or directly targeting NRF2therapies can push cancer cells beyond their limited oxidative buffering capacity