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MOTS-c safety data comes from animals plus one analog (CB4211) human Phase 1 trial

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2015;308(8):H86274

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Cysteine also plays important role in the metabolism of essential biochemicals such as coenzyme A, heparin, and biotin

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Daily weigh-ins create noise that obscures the signal

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New oral formulations, expanding coverage, and additional FDA approvals are likely to push utilization higher

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