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N Engl J Med 375:311322 Ahrn B, Masmiquel L, Kumar H, Sargin M, Karsbl JD, Jacobsen SH, Chow F (2017) Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial
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It reduces atherosclerotic plaque formation, inhibits the expression of vascular adhesion molecules, and prevents LDL-induced immune cell adhesion (2931)
A mitochondrial STAT3-methionine metabolism axis promotes ILC2-driven allergic lung inflammation
However, further research was not pursued due to the insufficient evidence of ipamorelin's efficacy in humans
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