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Correlation analysis was performed using R software (version 4.1.2, The R Foundation for Statistical Computing, Gut microbiome analyses Fecal samples were collected from WT mice ( n = 5) and Nrf2-KO mice ( n = 10) from the same litter, all of which had not been exposed to noise

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Reconstitution follows standard peptide preparation methods

[6] Methylene Blue also has pharmacological actions on signaling pathways, notably the nitric oxide (NO)-cyclic GMP pathway

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