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A dedicated MASLD trial is part of the broader TRIUMPH program

& Dorr, R.T

It does not explain FDA policy, does not name which 503B facility is retiring, and does not make any comparative claim between the old and new compounded product

Substantial fat mass loss after intensive weight loss will likely tend to reduce aromatase activity and regulate estradiol/testosterone equilibrium, resulting in decreased estradiol production, and will favor LH increase which contributes to stimulating testosterone production and substrate availability for estradiol production

It also acts to delay gastric emptying and suppress appetite, inducing weight loss by decreasing appetite and reducing food intake