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Hypothalamic neuronal preparations characterise the compound's effects on appetite-related circuits in the arcuate nucleus (POMC and AgRP neurons) and the paraventricular nucleus
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Palabras clave: GLP-1, diabetes mellitus, cardiovascular, liraglutida
Concomitant use of weight-promoting medications, such as insulin or sulfonylureas, may further blunt the weight loss effects of GLP-1 RAs [45]
Switching from Dulaglutide or Liraglutide to Semaglutide did not lead to a significant impact on HbA1c levels
In particular, glucagon-like peptide 1 (GLP-1) has gained enormous attention due to its insulinotropic action and relevance in the treatment of type 2 diabetes and obesity (1)
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