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Those who didnt have type 2 diabetes lost even more: an average of 16.9% compared to 9.9% in people with diabetes

Tolessa, T., Gutniak, M., Holst, J

Just how much of a challenge this posed can be gauged from the fact that Mutt's group needed 10km of porcine small intestine to obtain about 1mg of pure secretin (Rehfeld 2012)