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A large outcomes trial showed better weight loss and risk factor improvement compared with semaglutide, summarized in an American College of Cardiology trial review

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But that same triple action also means it touches more systems in the body

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The medium was removed and 125 I-GLP-1 (7-36) NH 2 (60 pM) or 125 I-GCG (40 pM) (PerkinElmer) and increasing concentrations unlabeled peptide agonists were added for overnight incubation at 4 C