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Transport of ALCAR across cell membranes, including the blood-brain barrier, is primarily mediated by the organic cation/carnitine transporter 2 (OCTN2, encoded by SLC22A5), a sodium-dependent transporter expressed on the luminal side of endothelial cells [5]
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Furthermore, GLP-1 RA-related NAEs are likely to occur in the early stages of treatment, mirroring the temporal trajectory of psychiatric 19 , gastrointestinal 36 , and ophthalmic 37 AEs associated with these agents, and emphasizing vigilance during treatment initiation phase
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