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The goal of this study was to compare the efficacy and safety of NASO B12 with oral methylcobalamin tablets in treating the deficiency of vitamin B12 in patients receiving metformin for the management of diabetes

Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)

Common signs include: Feeling tired all the time, even after sleeping well Brain fog or trouble focusing Forgetfulness or memory lapses Feeling low, anxious, or irritable Pins and needles in your hands or feet Pale or washed-out skin Weakness or loss of strength If its not treated, low B12 can eventually lead to nerve damage and other long-term health issues

My vision is blurry at night when Im tired also