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Think of titration like strength training
"Social media has led a lot of people to believe that weight loss drugs are magical bullets and they are not aware of the side effects," Yu said
Temperature: The recommended storage temperature is between 2C and 8C
Clinicians should: Assess baseline HbA1c and current glycemic control before discontinuation Implement or intensify alternative therapies (metformin, SGLT2 inhibitors, or other agents) before or concurrent with tirzepatide cessation Increase home glucose monitoring frequency for several weeks post-discontinuation Schedule follow-up to evaluate metabolic stability Special consideration for insulin or sulfonylurea users : Patients taking these medications alongside tirzepatide may need proactive dose adjustments when stopping tirzepatide to prevent hypoglycemia
Lodewyckx P, Issa J, Gaschignard M, et al
