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Abstract The pentose phosphate pathway (PPP) is a glucose-oxidizing pathway that runs in parallel to upper glycolysis to produce ribose 5-phosphate and nicotinamide adenine dinucleotide phosphate (NADPH)
Toxicity is not a risk
The numerous CF animal models that develop airway disease similar to humans [162,163,164,165], as well as the multiple small molecules available that inhibit or potentiate NPY signaling [182, 189] offer ample opportunities to investigate the potential role of NPY in CF
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It is a naturally occurring tripeptide found in human blood plasma, saliva, and urine
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