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Clinicians may prescribe them off-label for AUD or smoking cessation, but insurers can deny coverage and long-term safety data are still accruing

PMID 22616870

Researchers working with these compounds must comply with their institutional review board (IRB) requirements and applicable local and federal regulations

In subjects with CKD, particularly in cases of signs or symptoms suggestive of fluid retention, a long-acting loop diuretic such as torsemide [116] may be considered in addition or instead of a conventional thiazide-like agent (Fig

Weight loss was significantly greater with both doses of liraglutide than with placebo for all three primary endpoints