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FOXO4 is a member of the broader FOXO protein family, which has preserved both structural and functional characteristics across various animal species and has long been associated with pathways influencing aging

Collectively, this study provides a solid foundation for future exploration into the impact of NNMTi-and diet-mediated changes to the gut microbiome in obese and lean populations, as well as future targets to investigate mechanistically with NNMTi treatment

Cuproptosis, as a causal mechanism in Wilson disease, differs from other RCD types such as apoptosis, ferroptosis, necroptosis, and pyroptosis

Center for Disease Control and Prevention

Restoring the expression of VRK2 in VRK2-deficient cells made SLC7A11 redistribute to Golgi after BFA removal (Fig