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GLP-1 Receptor Agonists: Metabolic Regulators GLP-1 medications, including semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and liraglutide (Saxenda), suppress appetite, enhance insulin sensitivity, and promote weight loss by mimicking the incretin hormone GLP-1

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The two main culprits here are cortisol (the primary stress hormone) and prolactin