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This process occurs via two distinct pathways: heme iron, derived from animal sources, is internalized by enterocytes through the heme carrier protein 1 (HCP1), whereas non-heme iron, present in both plant and animal foods, must first be reduced from Fe 3+ to Fe 2+ form by ferrireductases such as duodenal cytochrome b (Dcytb) before it can be imported into the cell via the divalent metal transporter 1 (DMT1)

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