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However, based on the research to date, researchers will want to consider the following guidelines when when administering these peptides: Subcutaneous and intramuscular injections are considered more effective due to enhanced bioavailability , but using BPC-157 + TB-500 nasal spray could have certain advantages depending on the therapeutic objective and study design

Here is what we know, what we do not know, and where the gaps are

Moreover, oral BPC-157 has a low bioavailability and does not usually have a direct effect on tissues outside the gastrointestinal tract (e.g., tendons and nerves)

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Its believed it either works by activating other repair cells that can help tendons or ligaments or making the human growth factor receptor on these cells more sensitive (6)