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A Medline and Embase search was performed up to 31 January 2025 using the following search string: (obesity or overweight) AND (orlistat OR phentermine OR topiramate OR naltrexone OR bupropion OR liraglutide OR semaglutide OR tirzepatide)
This gives any residual medication on the oral mucosa additional time to absorb without being washed away by food or liquid
Some provide lyophilized powder that you reconstitute yourself, while others ship pre-mixed solutions ready for injection
A daily injection with Saxenda requires you to build a new habit
For guidance on managing this, our resource on GLP-1 constipation relief strategies offers practical solutions that apply to probiotic-induced constipation as well
