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Vitamin C is a white, crystalline, water-soluble substance found in citrus fruits

However, what we know so far is that the greatest utilization of these therapies have been observed in predominantly wealthy communities, which have comparatively lower rates of obesity and associated cardiometabolic conditions. Most of the data on these therapies thus far has been driven by clinical trials, which do not account for disruptions in medication adherence that often occur among everyday people

PMID 17070848

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doi: 10.3945/ajcn.114.086918 Summary Keywords nutritional interventions, osteoarthritis, metabolism, inflammation, oxidative stress, gut-joint axis Citation Wang Y, Cao Z, Gao Y, Shao P, Gao S, Dong M, Tian Z, Feng Y, Xu J and Xiang C (2025) Nutritional interventions for osteoarthritis: targeting the metabolism-inflammation-oxidative stress axisclinical evidence and translational practice