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Safety data from STEP UP demonstrated the tolerable profile of semaglutide 7.2 mg, with most signals mild-to-moderate gastrointestinal events, consistent with the glucagon-like peptide-1 receptor agonist (GLP-1 RA) class
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0.82 (95% CI 0.55-1.22) for a five-component MACE composite and 1.12 (95% CI 0.64-1.96) for three-component MACE
The Singapore Health Sciences Authority approved its use under similar guidelines, requiring proper medical supervision and regular monitoring throughout treatment
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