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While these therapies offer clear clinical value, they also bring complex messaging challenges

Gastroparesis and pulmonary aspiration risk GLP-1R agonists delay gastric emptying , leading to concerns about residual gastric content at the time of anaesthesia

[170] [171] In June 2025, the European Medicines Agency recommended that the product information for semaglutide medicines be updated to include non-arteritic anterior ischemic optic neuropathy (NAION) as a very rare side effect, [172] while the World Health Organization concluded that the risk management plan for semaglutide should be revised to include NAION as a potential risk

Its important to recognize these signs early and seek appropriate care

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