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People with existing kidney disease, those on diuretics, ACE inhibitors/ARBs, or NSAIDs, and older adults are particularly vulnerable
Overall prescribing trends The study found that 1,970,374 patients were prescribed a GLP-1 RA between January 2018 and March 2025, with 9,376,686 total prescriptions during this period
They work as off-label nutritional support a distinction that matters for setting realistic expectations
Patients should consult a pharmacist or GP before taking NSAIDs, particularly if experiencing dehydration from Wegovy's gastrointestinal side effects, as this may increase kidney injury risk [20] [15] Engage in gentle stretching exercises and low-impact activities like walking or swimming Maintain good posture during daily activities, particularly if sedentary work is involved As weight loss progresses on Wegovy, changes in body mechanics and centre of gravity may temporarily affect spinal loading patterns
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