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Exposure to pro-oxidant stimuli usually induces Nrf2 activation and upregulation of antioxidant enzyme expression through binding to the antioxidant response element (ARE), localized in the antioxidant enzyme gene promoters

[8] In summary, Methylene Blue has a broad interaction profile, with the most critical being its dangerous synergy with serotonergic drugs leading to serotonin syndrome

Journal of Food Science

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Disruption of the blood-brain barrier and neuronal cell death in cingulate cortex, dentate gyrus, thalamus, and hypothalamus in a rat model of Gulf-War syndrome