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2025;68:e240084

Science 370 , 861865 (2020)

Neurotrophins such as nerve growth factor, brain-derived neurotrophic factor and hepatocyte growth factor (HGF) are capable of stimulating dendritic arborization, synaptogenesis, stem cell differentiation, neurogenesis, and decreases in neuroinflammation, oxidative stress-induced damage and neurotoxicity due to a wide range of cellular insults

Concentrations of GSH, GSSG and the ratio between GSH and GSSG (GSH/GSSG), used as a proper value to evaluate the redox balance in these cells, are reported in Table 2

This sustained sensitivity may explain why some individuals report consistent benefits from low doses maintained over many months