Authors' contributions: JS and DF participated in the conception and design of the review, revised the whole manuscript, and read and approved the final manuscript
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
PMID: Summary Keywords Crohns disease, GLP, GLP-1, GLP-2 receptor agonist, IBD - inflammatory bowel disease, ulcerative colitis Citation Lee JJ, Bajgain P and Lightner AL (2026) GLP-1 and GLP-2 as intestinal reparative therapies in inflammatory bowel disease: mechanisms, translation, and clinical opportunity
But if you can just do that on your own and get mind over matter, it's the same thing." Lottie Moss Kate Moss' little sis revealed why getting on Ozempic was "the worst decision I ever made," during a September 2024 episode of her Dream On podcast
This multi-pathway approach helps explain why retatrutide's clinical effects exceed what would be predicted from simply adding the individual benefits of each receptor pathway